Peter L De Hoff

This study identifies VGLL1 as a key regulator of trophoblast development by integrating BMP, WNT, and HIPPO signaling through chromatin remodeling and transcriptional control in human stem cells.

The paper develops a scalable workflow for transcriptomic profiling of urinary exRNA during pregnancy, identifying differentially expressed exRNAs associated with pregnancy-related changes.

This study identifies and validates three bivariate extracellular miRNA biomarkers for early diagnosis and subtype distinction of preeclampsia using maternal serum samples.

This paper tests cleaning solutions for sentinel cards to improve temporal resolution of SARS-CoV-2 monitoring in schools by distinguishing new infections from persistent viral traces.

This study compares miRNA profiling methods using synthetic pools and exRNA samples, finding significant differences in reproducibility, accuracy, and sensitivity across platforms.