Josep Calafell-Segura

The paper establishes a cause-and-effect relationship between DNA methylation at the IL1RN promoter and gene expression, showing its impact on myeloid cell fate and inflammatory response.

The paper constructs a human microglia transcriptomic atlas, identifying 11 subpopulations across neurodegenerative conditions and revealing changes in homeostatic and disease-associated microglia subsets.

This study identifies epigenetic and transcriptomic changes in SLE monocyte subsets, linking them to disease activity and function.

This study shows ATP-mediated preconditioning induces epigenomic and transcriptomic changes in microglia-like cells that resemble epilepsy-associated microglial states.