Sarah M. Williams

This study identifies cell-type-specific carbon metabolism changes in poplar under combined abiotic stresses using multi-omics approaches.

This paper identifies a non-bifurcating NADH-dependent enzyme complex in anaerobic fungi responsible for H2 production, distinct from ferredoxin-dependent pathways.

This paper introduces a single-cell proteomics pipeline for analyzing human microglia, identifying 1039 proteins per cell and revealing mitochondrial protein variation across subtypes.

This paper develops a high-throughput single-cell proteomic method for PBMCs, achieving 660 cells per day with 750 protein identifications per cell and identifying low-frequency cell types.

This study applies single-cell proteomics to Arabidopsis leaf mesophyll cells to identify drought stress-related proteins and changes in protein networks.

The paper introduces nanoSPINS, a platform for high-throughput single-cell multiomics that integrates transcriptomic and proteomic profiling from the same cells, demonstrating improved throughput and statistical power.

This paper develops a spatial proteomics workflow to identify and map proteoforms in human kidney tissue, revealing spatially distinct proteomic profiles between glomeruli and tubules.