Author

Duhita Sengupta

Broad InstituteORCID 0000-0002-0232-379XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:Hi-C· 1 Assay:imaging· 1 Approach:simulation· 1

Frequent Co-Authors

Caroline UhleriD· 1 shared G. V. ShivashankariD· 1 shared Kaushik SenguptaiD· 1 shared Louis V. Cammarata· 1 shared Mithun Kumar MitraiD· 1 shared Rajshikhar Gupta· 1 shared Shreyasi Dey SarkariD· 1 shared Shuvadip DuttaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 16 mutual co-author links

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1 shared paperCell Biology

Caroline UhlerORCID

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2 papers

Recent·Most cited

Cell BiologyPLoS ONEPeer-reviewedOct 29, 2026

Adhesome Receptor Clustering is Accompanied by the Colocalization of the Associated Genes in the Cell Nucleus

Louis V. Cammarata, Duhita Sengupta, Rajshikhar Gupta…·G. V. Shivashankar

The paper shows that genes coding for adhesome receptor proteins are spatially co-localized and co-regulated in the nucleus, with transcription factors also co-localizing to reinforce extracellular matrix sensing.

DOI 10.1371/journal.pone.0361202

humanbulk RNA-seq

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BiophysicsNucleic Acids ResearchPeer-reviewedJun 13, 2025

Cardiomyopathic mutations of lamin A perturb mutual interactions of lamin, nuclear membrane, and chromatin leading to LLPS

Subhradip Nath, Shuvadip Dutta, Shreyasi Dey Sarkar…·Kaushik Sengupta

This study shows that cardiomyopathic lamin A mutations disrupt nuclear structure and chromatin organisation, leading to liquid-like aggregates and genome spatial disorganisation.

9 citations

humanimaging

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