Onofrio Laselva

This study benchmarks Trikafta's efficacy in CF patient-derived iPSC-derived colonic and airway tissues compared to isogenic controls, showing differential therapeutic responses.

The paper describes a high-throughput fluorescence-based assay to measure CFTR and other apical membrane protein activity in iPSC-derived intestinal organoids.

This paper describes a fluorescence-based platform for high-throughput Cystic Fibrosis therapy testing using iPSC-derived immature airway epithelium.

This study uses human pluripotent stem cells to model lung development, generating renewable lung epithelial spheroids and identifying new cell lineage relationships.