BioinformaticsNucleic Acids ResearchPeer-reviewed
fuNTRp: Identifying protein positions for variation driven functional tuning
Maximilian Miller, Dan Vitale, Peter C. Kahn…·Yana Bromberg
The paper introduces funtrp, a method to classify protein positions as neutral, rheostat, or toggle based on mutational impact, showing these types correlate with functional effects and improve variant effect prediction.
35 citations