Joanna Hicks

The paper shows Lig E increases transformation of N. gonorrhoeae with nuclease-damaged extracellular DNA, suggesting a role in overcoming environmental DNA degradation.

This study investigates the role of Lig E in Neisseria gonorrhoeae biofilm and microcolony formation, showing it enhances extracellular DNA ligation and matrix strength.

This study characterizes O-acetylserine sulfhydrylase (CysK) enzymes from bacteria without a sulfate reduction pathway, showing their substrate specificity and functional divergence in cysteine synthesis.

The paper identifies a novel inhibitor of serine acetyltransferase from Neisseria gonorrhoeae with an IC50 of 13.9 μM through virtual screening.

This study shows that Lig E in Neisseria gonorrhoeae is non-essential for DNA repair but plays a role in biofilm formation and extracellular DNA joining.