Author

Jack J. Riley

University of SheffieldORCID 0000-0002-0311-7787Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Christopher J. PriceiD· 2 shared Dylan StavishiD· 2 shared Ivana BarbariciD· 2 shared Owen LaingiD· 2 shared A. J. M. Gillis· 1 shared Alan Tin‐Lun LamiD· 1 shared Amy L. HardingiD· 1 shared Bethany M. JamesiD· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

Christopher J. PriceORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

GenomicsbioRxivPreprintJan 10, 2024

Widespread 3' UTR splicing regulates expression of oncogene transcripts in sequence-dependent and independent manners

Jack J. Riley, Cristina N. Alexandru-Crivac, Sam Bryce-Smith…·Ian M. Sudbery

The paper identifies widespread 3' UTR splicing in cancer, showing it regulates oncogene expression through NMD-dependent and -independent mechanisms, with specific examples in colon cancer.

DOI 10.1101/2024.01.10.575007

humanbulk RNA-seq

𝕏 PostBluesky

Cell BiologybioRxivPreprintDec 12, 2023

Aberrant Wnt activation in recurrent genetically variant human pluripotent stem cells impairs cardiomyocyte differentiation and phenotype

Theodore Wing, Christopher J. Price, Dylan Stavish…·Ivana Barbaric

This study shows that genetic variants in human pluripotent stem cells, specifically gains of chromosome 1q, impair cardiomyocyte differentiation and phenotype through aberrant Wnt activation.

2 citations

humanbulk RNA-seq

𝕏 PostBluesky

Cell BiologybioRxivPreprintSep 21, 2023

Cytogenetic resource enables mechanistic resolution of changing trends in human pluripotent stem cell aberrations linked to feeder-free culture

Dylan Stavish, Christopher J. Price, Gabriele Gelezauskaite…·Ivana Barbaric

The paper analyzes genetic changes in human pluripotent stem cells under different culture conditions and identifies a link between feeder-free culture and increased chromosome 1q gains.

8 citations

humanDNA methylation

𝕏 PostBluesky