N6-methyladenosine in DNA promotes genome stability
Brooke A. Conti, Leo Novikov, Deyan Tong…·Mariano Oppikofer
The paper identifies METTL3 and N6-methyladenosine (6mA) as factors promoting genome stability by repairing DNA base lesions.
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Rockefeller UniversityORCID 0000-0002-0320-0732Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
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Brooke A. Conti, Leo Novikov, Deyan Tong…·Mariano Oppikofer
The paper identifies METTL3 and N6-methyladenosine (6mA) as factors promoting genome stability by repairing DNA base lesions.
Brooke A. Conti, Penelope D. Ruiz, Cayla Broton…·Agata Smogorzewska
This study shows RTF2 regulates replication repriming and ribonucleotide excision at the replisome, ensuring efficient replication restart and preventing replication stress.
Supawat Thongthip, Brooke A. Conti, Francis P. Lach, Agata Smogorzewska
This study shows that inhibiting NHEJ components does not rescue DNA repair defects in FA patient cells, with only partial suppression of chromosomal abnormalities by 53BP1 knockout.