Vincent Soubannier

The paper establishes a validated antibody platform for ALS research, identifying high-quality antibodies and revealing protein expression patterns in neurological cell types.

The paper develops a SOX10 reporter system to improve the differentiation of oligodendrocytes from iPSCs, enhancing reproducibility and maturity.

This study identifies early nuclear phenotypes in SOD1-mutated astrocytes derived from ALS patients that precede reactive transformation and may affect astrocyte-MN communication.

This study compares FMR1 knock-out and Fragile X patient iPSC-derived neuronal models, finding shared transcriptional and functional impairments in neuronal activity and differentiation.

The paper develops a flow cytometry pipeline called CelltypeR to annotate and characterize cell types in brain organoids, identifying dopamine neuron subtypes and tracking cell type dynamics over time.

This study develops a method to rapidly generate ventral spinal cord-like astrocytes from human iPSCs to model lower motor neuron disease mechanisms.

This study uses midbrain organoids from SNCA triplication patients to model synucleinopathy features, showing increased alpha-synuclein expression and aggregation linked to dopaminergic neuron loss.

This study derives and characterizes human iPSC-derived astrocytes, showing they exhibit physiological traits and respond to inflammatory stimuli, making them suitable for disease modeling and drug discovery.