Thibaut Larcher

This study shows that intracellular accumulation of AAV6 genomes in microglia drives reactivity and inflammation in retinal gene therapy.

This study compares the pathogenesis of NiV-Malaysia and NiV-Bangladesh strains in IFNAR KO mice, showing differential outcomes based on infection route and strain.

This study identifies MARK2 as a gatekeeper of CD28-dependent co-stimulation in T cells, showing it restricts metabolic and transcriptional programs normally driven by CD28.

This study enhances liver gene therapy by conjugating GalNAc to rAAV capsids, improving transduction efficiency in mice while reducing required dosages.

This study shows that combining aerosolized FLAMOD with subtherapeutic penicillin G improves bacterial clearance and reduces lung lesions in pigs infected with Actinobacillus pleuropneumoniae.

This study investigates the effects of iron deficiency and overload on SARS-CoV-2 lung infection in mice, finding modest inflammatory changes but no significant disease exacerbation.

The paper shows that conserved RNA-binding protein interactions mediate the function of syntologous lncRNAs despite lacking sequence similarity.

This study shows that microplastics co-delivered with SARS-CoV-2 in mice suppress early innate immune responses but promote a cytokine release syndrome signature later in infection.