Caroline Tapparel

The paper examines ex vivo airway epithelial cultures from transplant recipients to identify epithelial changes associated with bronchiolitis obliterans syndrome.

This study uses human airway organoids to screen 764 natural plant extracts for antiviral activity against RSV, identifying 45 active compounds with distinct mechanisms.

The paper uses single-cell RNA sequencing to identify epithelial dysfunction, inflammation, and premature aging in airway epithelium from transplant recipients, linking these features to bronchiolitis obliterans syndrome.

This paper describes a method to generate apical-out nasal organoids from nasal epithelial cells, which can be used for studying viral infections and drug responses.

This study shows that EV-A71 adapts to heparan sulfate by losing pH-dependent uncoating, which compromises capsid stability and affects viral fitness in vivo.

This study develops CD-SA, a β-cyclodextrin-based nanomaterial that acts as a potent broad-spectrum antiviral against influenza A and B viruses, showing higher efficacy than Oseltamivir in ex vivo and in vivo tests.

This study evaluates a combined anti-influenza therapy using single cell RNA sequencing to show its effectiveness in inhibiting viral replication across different epithelial cell types.