Author

Leslie J. Parent

Pennsylvania State UniversityORCID 0000-0002-0431-9049Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cell signaling & trafficking· 2 Approach:microscopy & imaging analysis· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Gregory S. LambertiD· 2 shared Rebecca J. Kaddis MaldonadoiD· 2 shared Breanna L. RiceiD· 1 shared Christopher A. SiedleckiiD· 1 shared Jordan T. ChangiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 7 mutual co-author links

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2 shared papersBiophysics

Gregory S. LambertORCID

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3 papers

Recent·Most cited

MicrobiologymBioPeer-reviewedAug 19, 2025

Dynamic interactions of retroviral Gag condensates with nascent viral RNA at transcriptional burst sites: implications for genomic RNA packaging

Rebecca J. Kaddis Maldonado, Leslie J. Parent

This study uses live cell imaging to show that RSV Gag transiently interacts with nascent USvRNA at transcriptional burst sites in the nucleus, supporting a model of dynamic gRNA selection for packaging.

1 citation

imagingmicroscopy & imaging analysis

𝕏 PostBluesky

BiophysicsInternational Journal of Molecular SciencesPeer-reviewedJun 13, 2025

Two peas in a pod: retroviral RNA dimers organize Gag-RNA nanoclusters with novel biophysical properties

Gregory S. Lambert, Christopher A. Siedlecki, Leslie J. Parent

This study uses AFM and FCS to investigate the role of gRNA dimerization in the structure and stability of RSV Gag-vRNA biomolecular condensates.

1 citation

proteomicsmicroscopy & imaging analysis

𝕏 PostBluesky

MicrobiologyRetrovirologyPeer-reviewedJun 19, 2024

Comparative analysis of retroviral Gag-host cell interactions: focus on the nuclear interactome

Gregory S. Lambert, Breanna L. Rice, Rebecca J. Kaddis Maldonado…·Leslie J. Parent

This study compares the nuclear interactomes of HIV-1 and RSV Gag proteins, identifying shared and unique host factors involved in nuclear processes like transcription and chromatin remodeling.

6 citations

humanproteomics

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