Manuel A. S. Santos

This study develops a proteogenomic pipeline to detect amino acid misincorporation in Candida albicans and shows increased misincorporation at CUG sites without affecting other codons.

The paper integrates differential gene expression with WGCNA to identify aging-related expression signatures in mouse tissues, revealing common proteostasis pathways across multiple organs.

The paper shows that mutations in tRNA-modifying enzymes in yeast lead to mistranslation and protein aggregation by affecting specific tRNA modifications.