Logan Mulroney

The paper demonstrates that long-read RNA-seq with quality control measures reduces bias in allele counts across four species, improving accuracy in allelic imbalance studies.

The paper uses direct RNA nanopore sequencing to identify RNA modification changes in human pancreatic beta-cells after glucose stimulation, finding 1,697 differentially modified sites linked to type 2 diabetes genes.

The paper introduces an IVT-based method with dRNA-seq to detect RNA modifications across the transcriptome, identifying 26,619 modification sites and revealing non-random co-occurrence and isoform-specific patterns.

The paper identifies host proteins interacting with SARS-CoV-2 RNA ends, highlighting pseudouridine synthase PUS7 and post-transcriptional modifications in viral RNA structure and function.

This study introduces NRCeq, a method to identify capped full-length SARS-CoV-2 transcripts, revealing new insights into sgRNA structure and expression.

The paper identifies high-confidence full-length human RNA isoform scaffolds using nanopore sequencing by improving 5' cap detection and 3' polyadenylation site identification.

This paper tests the use of Cid1 to add poly(I) tails to RNA for direct nanopore sequencing, enabling detection of both poly(A) and non-poly(A) RNAs and nascent transcripts.

This paper uses nanopore direct RNA sequencing to detect modified nucleotides in 16S rRNA, revealing a 7-methylguanosine modification linked to aminoglycoside resistance in E. coli.