Molecular BiologyMolecular CellPeer-reviewed
Hyperosmotic stress induces downstream-of-gene transcription and alters the RNA Polymerase II interactome despite widespread transcriptional repression
Nicolle A. Rosa-Mercado, Joshua T. Zimmer, Maria Apostolidi…·JOAN ARGETSINGER STEITZ
The paper shows hyperosmotic stress causes transcriptional repression but still leads to downstream-of-gene (DoG) transcripts, with Pol II interactome changes and Integrator complex disruption involved.
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