Suzanne Walker

This study investigates the effects of O-GlcNAc depletion on lipid metabolism and shows that it leads to lipid remodeling and increased sensitivity to ferroptosis.

This study investigates MOMP assembly in Corynebacterium glutamicum, showing that PorH and ProtX are inserted at polar growth zones and linked to the cell wall.

This paper identifies the TmaT-AftD interaction as essential for mycolate transport via the CmpL4 pathway and AG synthesis in Corynebacterium glutamicum.

This study identifies NagU as the primary uridyltransferase in Staphylococcus aureus for UDP-GlcNAc synthesis, which is essential for cell wall synthesis and regulated by its interaction with DacA.

This study identifies BilR and BilV as enzymes involved in the branched microbial metabolism of bilirubin to urobilinogen in the human gut.

This study elucidates the mechanism of MBOAT-SGNH acyltransferases in Gram-negative bacteria, showing that a tyrosine-containing peptide shuttles acyl groups from MBOAT to SGNH active sites for peptidoglycan O-acetylation.

This study identifies LTA's role in regulating ScaH to maintain cell wall integrity in S. aureus, showing that LTA suppresses ScaH expression and activity while sequestering it during growth.

The paper identifies an activation pathway involving PBP2 that enhances cell wall polymerization and MreB filament formation in E. coli.

The paper shows that LDT-mediated crosslinks in mycobacteria are crucial for maintaining rod shape at aging cell wall sites, and their absence makes Mtb more susceptible to combined PBP and LDT-inhibiting drugs.

The paper shows MreB filaments align along principal membrane curvature to create rod shape in bacteria, supported by biophysical modeling and experimental observations.