Locus coeruleus degeneration is associated with cortical tau deposition and cognitive decline in older adults at familial risk of Alzheimer's disease
Alfie R. Wearn, Kate M. Onuska, Hayley R. C. Shanks…·R. Nathan Spreng
Author
Montreal Neurological Institute and HospitalORCID 0000-0002-0632-4060Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
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Alfie R. Wearn, Kate M. Onuska, Hayley R. C. Shanks…·R. Nathan Spreng
Colleen S. Hughes, Anne C. Krendl, Roberto C. French…·Richard F. Betzel
This study shows that individualized functional brain network mapping in older adults reveals more heterogeneity and improves network fidelity compared to group-averaged approaches.
Roni Setton, Laetitia Mwilambwe-Tshilobo, Manesh Girn…·R. Nathan Spreng
This study examines age-related changes in brain functional architecture using multi-scale fMRI analyses in younger and older adults, finding both global and network-specific dedifferentiation patterns.