Author

Xinru Zhang

Pennsylvania State UniversityORCID 0000-0002-0633-2888Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Xinru Zhang1 paper · Chinese Academy of Sciences

Biology Disciplines

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Evolutionary Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:whole-genome sequencing· 2 Organism:chicken / avian· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:database / resource· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Kateryna D. MakovaiD· 2 shared Adam M. PhillippyiD· 1 shared Alexander P. SweeteniD· 1 shared Alexandra P. LewisiD· 1 shared Alice YoungiD· 1 shared Amalia Dutra· 1 shared Andrew W. CarrolliD· 1 shared Arang RhieiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersEvolutionary Biology

Kateryna D. MakovaORCID

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2 papers

Recent·Most cited

Evolutionary BiologyGenome Biology and EvolutionPeer-reviewedFeb 21, 2026

Substitution spectrum and selection at G-quadruplexes in great ape telomere-to-telomere genomes

Xinru Zhang, Saswat K. Mohanty, Francesca Chiaromonte, Kateryna D. Makova

This study analyzes substitution patterns and selection at G-quadruplexes in great ape genomes, finding stronger purifying selection on stems than loops, especially in regulatory regions.

2 citations

humanchicken / avian

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GenomicsNaturePeer-reviewedMay 29, 2024

The Complete Sequence and Comparative Analysis of Ape Sex Chromosomes

Kateryna D. Makova, Brandon D. Pickett, Robert S. Harris…·Adam M. Phillippy

The paper produces gapless assemblies of ape sex chromosomes for five great apes and a lesser ape, revealing divergence in Y chromosomes and evolutionary dynamics.

122 citationstop 1%

humanwhole-genome sequencing

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