Synthetic BiologybioRxivPreprint
Nonenzymatic loop-closing ligation generates RNA hairpins and is a template-free way to assemble functional RNAs
Long-Fei Wu, Ziwei Liu, Samuel J. Roberts…·John D. Sutherland
This study demonstrates nonenzymatic loop-closing ligation can assemble functional RNA hairpins without templates, enabling the formation of complex RNA structures.
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