Grace Arhin

This study reveals the molecular mechanism of nirmatrelvir binding to SARS-CoV-2 main protease using combined NMR titrations and weighted ensemble simulations, identifying two distinct binding pathways and key residues involved in resistance.

The paper identifies eight small molecules that bind to NPSL2, a regulatory element in oncomiR-1, using virtual screening and experimental validation.

The paper identifies novel ligands that bind to the Dicer cleavage site of pre-miR-31 through in silico screening and experimental validation.