Author

Stefan Oliver Bassler

European Molecular Biology LaboratoryORCID 0000-0002-0652-9242Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Athanasios TypasiD· 2 shared Adam J. MulkerniD· 1 shared Kiran Raosaheb PatiliD· 1 shared Natalia GabrielliiD· 1 shared R. Craig MacLeaniD· 1 shared Sergej AndrejeviD· 1 shared Vinita PeriwaliD· 1 shared William MatlockiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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2 shared papersMicrobiology

Athanasios TypasORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintFeb 20, 2026

DNA-damaging combination treatments impose genotype-specific constraints on hypermutator evolvability

Adam J. Mulkern, Stefan Oliver Bassler, William Matlock…·R. Craig MacLean

This study shows that combining DNA-damaging agents with antibiotics can reduce resistance evolution in specific hypermutator bacterial genotypes but not others.

DOI 10.64898/2026.02.20.706947

E. coliwhole-genome sequencing

𝕏 PostBluesky

BioinformaticsbioRxivPreprintNov 6, 2020

Bioactivity assessment of natural compounds using machine learning models based on drug target similarity

Vinita Periwal, Stefan Oliver Bassler, Sergej Andrejev…·Athanasios Typas

This paper develops a machine learning model to predict protein targets of natural compounds based on drug target similarity, identifying potential therapeutics with experimental validation.

1 citation

machine learning (classical)drug response / drug discovery

𝕏 PostBluesky