Omar E. Franco

This study shows that mTOR inhibition with everolimus enhances antitumor immune responses in TP53-mutant HNSCC by altering the tumor microenvironment.

This study identifies MYCL as a key driver of neuroendocrine lineage programs in prostate cancer by showing its upregulation in NEPC and its role in suppressing AR signaling and inducing neuroendocrine reprogramming.

The paper links an age-associated CD8+ T cell subset to symptomatic benign prostatic hyperplasia through immune aging mechanisms.

The paper identifies lipid-rich macrophage subpopulations in BPH that correlate with prostate size and urinary symptoms.

This paper introduces a high-throughput method to generate human prostate tissue from induced pluripotent stem cells using co-culture with urogenital sinus mesenchyme.

This study develops a hybrid model showing stromal reactivity influences prostate cancer progression and prognosis by shaping tumor cell evolution and aggressiveness.