Cancer BiologyBiology OpenPeer-reviewed
Tuneable hydrogel stiffness in a 3D in vitro model induces epithelial to mesenchymal transition in MCF7 but not MDA-MB-231 breast cancer cells
Jessika Wise, Margaret J. Currie, Tim B. F. Woodfield…·Elisabeth Phillips
This study shows that MCF7 breast cancer cells undergo epithelial-to-mesenchymal transition in stiff hydrogels, while MDA-MB-231 cells do not, highlighting the role of matrix stiffness in cancer progression.
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