Author

Carolina Borsoi Moraes

Universidade de São PauloORCID 0000-0002-0689-2770Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Antônio Moreira Marques-Neto· 1 shared Bertal Huseyin AktasiD· 1 shared Bruno Rafael BarbozaiD· 1 shared Camila Colombari Mantovani· 1 shared Cláudia Blanes AngeliiD· 1 shared Cristiane Moutinho-Melo· 1 shared Deivid Martins SantosiD· 1 shared Denise R. B. Pilger· 1 shared

Activity by Year

2017-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperMicrobiology

Antônio Moreira Marques-Neto

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3 papers

Recent·Most cited

BiochemistrybioRxivPreprintFeb 2, 2025

Ultra-high throughput in vitro translation assay for identification of Trypanosoma cruzi-specific protein synthesis inhibitors

Camila Colombari Mantovani, Carolina Borsoi Moraes, Guilherme Rodrigo Reis Monteiro dos Santos…·Sérgio Schenkman

This paper develops an ultra-high throughput in vitro translation assay for identifying T. cruzi-specific protein synthesis inhibitors and identifies quinazoline compounds that inhibit translation in both the assay and live parasites.

DOI 10.1101/2025.02.02.636133

experimental assaydrug response / drug discovery

𝕏 PostBluesky

MicrobiologyPLoS neglected tropical diseasesPeer-reviewedSep 25, 2024

ST8Sia2 polysialyltransferase protects against infection by Trypanosoma cruzi

Bruno Rafael Barboza, Janaína Macedo-da-Silva, Lays Adrianne Mendonça Trajano-Silva…·Giuseppe Palmisano

This study shows that ST8Sia2 polysialyltransferase reduces Trypanosoma cruzi infection by modulating host polysialylation.

1 citation

humanproteomics

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MicrobiologybioRxivPreprintNov 27, 2017

Drug repurposing for yellow fever using high content screening

Denise R. B. Pilger, Carolina B. Moraes, Laura H. V. Gil, Lucio H. Freitas-Junior

This study screens a compound library to identify anti-yellow fever drugs, finding 88 compounds effective against YFV and 18 against DENV, with 12 overlapping, suggesting potential for broad antiviral therapies.

DOI 10.1101/225656

humanexperimental assay

𝕏 PostBluesky