PhysiologyThe Journal of General PhysiologyPeer-reviewed
Carboxyl Terminal Domain Missense Mutations Alter Distinct Gating Properties of the Cardiac Sodium Channel
Akshay Sharma, Christopher Marra, Nomon Mohammad…·Mitchell P. Goldfarb
This study investigates how missense mutations in the CTD of Nav1.5 affect gating properties, revealing distinct effects on inactivation and activation.
DOI 10.1085/jgp.202513835