Cancer BiologyOncogenePeer-reviewed
PTEN neddylation aggravates CDK4/6 inhibitor resistance in breast cancer
Fan Liu, Weixiao Liu, Yawen Tan…·Ping Xie
This study shows that PTEN neddylation promotes resistance to CDK4/6 inhibitors in breast cancer by activating the PI3K/Akt pathway and AP-1 transcription factor, and identifies Echinacoside as a potential inhibitor.
5 citations