Whole genome CRISPR knockout screen reveals ID3 as a key regulator of myeloma cell survival via TCF3 and c-MYC
Clara Andersson-Rusch, Md. Abu Hanif, Ingrid Quist-Løkken…·Toril Holien
Author
Australian National UniversityORCID 0000-0002-0768-7920Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
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Clara Andersson-Rusch, Md. Abu Hanif, Ingrid Quist-Løkken…·Toril Holien
Rebecca A. Jaeger, Nadia A. Roberts, Cynthia M. Turnbull…·Anselm Enders
This study shows that a heterozygous IRF4L116R mutation selectively impairs CD4 T cell differentiation into Th1, Th17, and Treg subsets, protecting against neuroinflammation without affecting overall T cell activation or memory.
Rebekah G. Parkinson, Tony Xu, Jacob Martin…·Nathalie Dehorter
This study shows that autoimmune response to alpha-synuclein antigen causes Parkinson's disease-like symptoms in mice through immune cell infiltration and inflammation.
Helle Samdal, Siv Anita Hegre, Konika Chawla…·Pål Sætrom
This study shows that SNHG26, a G2-phase enriched lncRNA, is necessary for cell cycle progression and proliferation, with effects on mitochondrial stress and gene expression.