PathologyCellular & Molecular Biology LettersPeer-reviewed
The SARS-CoV-2 envelope PDZ Binding Motif acts as a virulence factor disrupting host's epithelial cell-cell junctions
Flavio Alvarez, Guilherme Dias de Melo, Florence Larrous…·Célia Caillet‐Saguy
This study shows that the SARS-CoV-2 E protein's PDZ-binding motif enhances virulence by disrupting epithelial barriers and inflammation, but not neuroinvasion.
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