Author

Jörg Piontek

Charité – Universitätsmedizin BerlinORCID 0000-0002-0880-8915Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Arbesa Saiti· 1 shared Daniel RodereriD· 1 shared Hannes GonschioriD· 1 shared Joy Weber· 1 shared Marie Bieck· 1 shared Martin LehmanniD· 1 shared Rozemarijn E. van der VeeniD· 1 shared Santhosh Kumar NagarajaniD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 13 mutual co-author links

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1 shared paperCell Biology

Arbesa Saiti

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2 papers

Recent·Most cited

BioinformaticsComputational and Structural Biotechnology JournalPeer-reviewedDec 2, 2024

C. perfringens enterotoxin-claudin pore complex: Models for structure, mechanism of pore assembly and cation permeability

Santhosh Kumar Nagarajan, Joy Weber, Daniel Roderer, Jörg Piontek

The paper models the structure and mechanism of the CPE-claudin-4 pore complex, revealing its hexameric architecture and cation selectivity.

4 citations

protein structurestatistical model

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Cell BiologyJournal of Biological ChemistryPeer-reviewedAug 17, 2024

Claudin-4 polymerizes after the incorporation of just two extracellular claudin-3 residues

Rozemarijn E. van der Veen, Jörg Piontek, Marie Bieck…·Martin Lehmann

This study identifies key residues in claudin-4 that enable polymerization when supplemented with claudin-3 residues, enhancing tight junction formation and barrier function.

11 citations

humanproteomics

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