Anna Krook

This study examines how different exercise intensities affect the human plasma secretome and interorgan communication through multi-cohort interventions and multi-organ gene expression analysis.

This study identifies TMEM9B-AS1, a human-specific lncRNA downregulated in type 2 diabetes skeletal muscle, which regulates ribosomal biogenesis by stabilizing MYC mRNA through interaction with IGF2BP1.

This study shows that reduced NR4A3 levels in skeletal muscle due to inactivity impair glucose metabolism, translation, and myotube size by affecting mTORC1 and ribosomal pathways.

The paper uses proteomics to identify personalized signatures of insulin resistance and type 2 diabetes, showing that fasting proteome and phosphoproteome predict insulin sensitivity and reveal sex-specific differences.

The paper shows that reduced CKMT2 impairs mitochondrial function in type 2 diabetes, independent of insulin action.

This study identifies miR-29a-3p as a myokine secreted during resistance exercise that coordinates metabolic responses and miRNA expression in muscle and liver.