Henrik Clausen

The paper describes methods to make a membrane-bound glycosyltransferase water-soluble for easier study and application in synthetic glycobiology.

This study identifies that Siglec-7 and -15 recognize repeated clustered sulfo-sialo O-glycan motifs on specific O-glycoproteins, enhancing selectivity through multivalent interactions.

The paper identifies O-mannosylation and protein maturation as therapeutic targets in BRAF fusion oncogenesis by showing their necessity for fusion-induced transformation.

This study identifies biantennary N-glycans as receptors for MARTX toxins in Vibrio vulnificus, showing their role in pathogenesis and broad cell targeting.

The paper shows that growth factors induce rapid desialylation of cell surface glycoproteins, enabling reversible changes in glycan structure and function through galectin-mediated endocytosis.