BiochemistryJournal of Biological ChemistryPeer-reviewed
Identification of PS1/gamma-secretase and glutamate transporter GLT-1 interaction sites
Florian Perrin, Priyanka Sinha, Shane Mitchell…·Oksana Berezovska
This study identifies interaction sites between PS1/gamma-secretase and GLT-1 using alanine scanning and FLIM, validated by AlphaFold Multimer, and demonstrates CPPs can disrupt this interaction in neurons.
3 citations