Author
Brigham and Women's HospitalORCID 0000-0002-0943-7407Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Dennis H. Gong, Jimmy A. Guo, Jennifer Su…·William L. Hwang
This study identifies Glis3 as a key transcription factor driving metastasis in PDAC by promoting a neural-like progenitor cell state.
Yetiş Gültekin, Sharanya Sivanand, Kian Moritz Eghbalian…·Matthew G. Vander Heiden
This study shows pancreatic cancer disrupts normal pancreatic function, leading to systemic nutrient depletion and muscle wasting, with autophagy in muscle playing a key role in nutrient redistribution to support tumor growth.
James R. Lindsay, Jennifer Altreuter, Joao V. Alessi…·William E. Lotter
The paper provides a pan-cancer spatial analysis of immune biomarkers in the tumor microenvironment using multiplex immunofluorescence data from 2,019 tumors across 14 cancer types.
Katie E. Blise, Shamilene Sivagnanam, Courtney B. Betts…·Katelyn T. Byrne
This study uses machine learning to analyze spatial proteomic data from pancreatic cancer patients, linking T cell function and localization to neoadjuvant CD40 therapy and clinical outcomes.