Gabriel A. Rabinovich

This study identifies a developmental GAL1-glycan program that promotes early breast cancer dissemination and metastasis by reactivating mammary stem cell traits and epithelial plasticity.

This paper identifies how KSHV alters mesenchymal cell glycosylation to enhance PDGFRA signaling, contributing to Kaposi sarcoma pathogenesis.

This study shows that reduced (2,6)-sialylation in SIgA and B cells during UC impairs their function and exacerbates intestinal inflammation.

This study shows that galectin-1 modulates cell adhesions, caveolae, and vascular permeability in kidney endothelial cells through proteomic and phosphoproteomic analyses.

This paper identifies Galectin-3 as a key regulator of amyloid-beta aggregation and microglial dysfunction in Alzheimer's disease, showing its role in neurotoxicity and potential as a therapeutic target.

This study identifies a pro-inflammatory stem cell niche that drives myelofibrosis via galectin 1, offering a targetable pathway for therapy.

MIXTURE improves immune tumor microenvironment estimation by reducing overestimation of cell-type counts and improving accuracy in bulk RNA data.