Anandi Krishnan

This study compares platelet and leukocyte transcriptomes in MPN patients, finding platelets better capture myelofibrosis signatures and provide more accurate diagnosis.

The paper profiles the platelet proteome in MPN patients to identify mediators of thrombosis and proteostasis, validating key transcriptome findings.

This study quantifies coagulation changes after traumatic injury and links them to injury severity and mortality.

This study shows that the CD47-SIRP axis regulates platelet homeostasis and that blocking this interaction affects platelet levels in mice and humans.

This study identifies a pro-inflammatory stem cell niche that drives myelofibrosis via galectin 1, offering a targetable pathway for therapy.

This paper identifies 32 genes with altered expression in platelets from MPN patients, linking them to thrombosis and bleeding risks, and suggests clinical applications for risk stratification and treatment tailoring.

The paper identifies platelet transcriptome markers for predicting disease progression in MPNs and develops a machine learning model to predict advanced MF with high accuracy.