Marius Schmidt

This study uses cryo-EM to determine the structure of a light-regulated bacterial two-component system, revealing how light affects signaling through changes in histidine kinase and response regulator interactions.

KINNTREX uses a neural network to predict chemical kinetic mechanisms from time-resolved X-ray crystallography data without requiring candidate mechanisms.

The paper reports Cryo-EM structures of bacterial phytochromes in different light states, revealing insights into their signaling mechanisms.

The paper uses MISC to study Sulbactam inhibition of M. tuberculosis BlaC, revealing heterogeneity, cooperativity, and conformational changes in atomic detail.