Oscar Vivas

This paper develops a new methodology to model phosphoinositide signaling dynamics, showing that basal PI(4)P levels determine cell-specific responses to genetic perturbations.

This study investigates how cholesterol, PtdIns(4,5)P2, and actin regulate BK channel nanoscale organization using super-resolution imaging and FRAP in heterologous and endogenous systems.

The paper shows BK and CaV1.3 channels begin assembling into hetero-clusters intracellularly before reaching the plasma membrane.

This study shows that aging affects sympathetic motor neurons, increasing their firing responses and reducing M current, contributing to sympathetic overactivity in older mice.