GenomicsNature GeneticsPeer-reviewed
Deep learning enables genetic analysis of the human thoracic aorta
James P. Pirruccello, Mark D. Chaffin, Elizabeth L. Chou…·Patrick T. Ellinor
This study uses deep learning to analyze aortic dimensions from MRI and identifies genetic loci associated with aortic diameter, highlighting SVIL as a key gene and developing a polygenic score for aneurysm risk.