BiophysicsNature CommunicationsPeer-reviewed
Disulfide constrained Fabs overcome target size limitation for high-resolution single-particle cryo-EM
Jennifer E. Kung, Matthew Camp Johnson, Dimitry Tegunov…·Jawahar Sudhamsu
This paper introduces Rigid-Fabs, disulfide-constrained antibody fragments that enable high-resolution cryo-EM structures of small proteins by overcoming size limitations.
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