Govind Menon

The paper shows how COOLAIR co-transcriptional dynamics integrate temperature fluctuations to repress FLC through chromatin regulation.

This study uses pPOINT-seq to analyze co-transcriptional splicing in Arabidopsis, finding that cold exposure globally enhances splicing and alters intron processing patterns.

The paper investigates cold-induced repression of FLC in Arabidopsis, finding distinct mechanisms involving splicing changes and reduced transcription initiation, separate from warm-induced repression.

The paper develops a computational model to explain how proximal termination influences the rate of Polycomb silencing establishment at the FLC locus in Arabidopsis.

The paper shows that antisense transcription and PRC2 silencing work together to regulate FLC during vernalization, with different response dynamics influenced by temperature and growth conditions.

The paper shows that FLC gene expression in Arabidopsis is regulated by both analog and digital modes before cold exposure, with analog preceding digital and leading to gradual repression.