BioinformaticsbioRxivPreprint
Stromal signals dominate gene expression signature scores that aim to describe cancer-intrinsic stemness or mesenchymality characteristics
Julian Kreis, Bogac Aybey, Felix Geist…·Eike Staub
The paper shows that stromal cells, particularly fibroblasts, dominate EMT-related gene expression signature scores in cancer, rather than tumor-intrinsic properties.
DOI 10.1101/2023.08.25.554747