Author

Thierry Gostan

Centre National de la Recherche ScientifiqueORCID 0000-0002-1087-8015Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Adèle L’Hostis· 1 shared Alja Kozulic-Pirher· 1 shared Amal Zine El AabidineiD· 1 shared Camille BellièresiD· 1 shared Édouard BertrandiD· 1 shared Encar García-OliveriD· 1 shared Eugenia I. BasyukiD· 1 shared Florian MuelleriD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperSystems Biology

Adèle L’Hostis

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJul 1, 2026

RNA dysregulation and compromised neuronal identity drive pathogenesis in Senataxin-associated ALS

Marta Giannini, Thierry Gostan, Amal Zine El Aabidine…·Odil Porrúa

This study investigates how SETX mutations in ALS4 lead to RNA dysregulation and neuronal dysfunction through TGF-β signaling activation and R-loop metabolism disruption.

DOI 10.64898/2026.06.30.735532

humanbulk RNA-seq

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Systems BiologyNature CommunicationsPeer-reviewedJul 23, 2021

Stochastic pausing at latent HIV-1 promoters generates transcriptional bursting

Katjana Tantale, Encar García-Oliver, Marie-Cécile Robert…·Édouard Bertrand

The paper uses single molecule imaging to study HIV-1 promoter pausing and finds that stochastic pausing leads to transcriptional bursting in latent cells.

75 citationstop 2%

humanexperimental assay

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