Inmaculada Spiteri

This study shows that immune evasion in colorectal cancer follows a 'Big Bang' pattern, where early genetic and epigenetic changes drive subsequent tumor-immune evolution.

This paper demonstrates evolutionary herding in non-small cell lung cancer to control drug resistance by shifting clonal composition and inducing collateral sensitivity.

This study measures single-cell division rates and survival in human cancers using multi-region sequencing data, revealing per-cell mutation and survival rates across different cancer types and healthy tissues.