Molecular BiologybioRxivPreprint
Lipid-Mediated Control of ER Function During Apoptosis
José Luis Garrido-Huarte, Josep Fita‐Torró, Amparo Pascual‐Ahuir, Markus Proft
The paper shows how the sphingolipid-derived aldehyde t-2-hex induces ER stress and mitochondrial dysfunction, leading to apoptosis in yeast, with Fmp52/Tip30 as a protective factor.
DOI 10.1101/2025.12.01.691522