Author

Ian Timothy Sembiring Meliala

Chongqing UniversityORCID 0000-0002-1136-6994Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Christopher G. ProudiD· 1 shared Hezhao Zhao· 1 shared Jingyuan CheniD· 1 shared Ling ChengiD· 1 shared Makoto MiyagishiiD· 1 shared Mankun Wei· 1 shared Mikael BjörklundiD· 1 shared Rendy HoseaiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

Christopher G. ProudORCID

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2 papers

Recent·Most cited

Cell BiologyeLifePeer-reviewedJan 29, 2025

PEBP1 amplifies mitochondrial dysfunction induced integrated stress response

Ling Cheng, Ian Timothy Sembiring Meliala, Yidi Kong…·Mikael Björklund

This study identifies PEBP1 as a mediator of mitochondrial stress response by enhancing eIF2 phosphorylation and ISR gene expression.

9 citations

humanproteomics

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Cancer BiologyAdvanced SciencePeer-reviewedApr 29, 2024

YY2/BUB3 axis-mediated SAC hyperactivity determines tumor cell fate through chromosomal instability

Rendy Hosea, Wei Duan, Ian Timothy Sembiring Meliala…·Vivi Kasim

This study identifies the YY2/BUB3 axis as a regulator of SAC activity and shows how SAC hyperactivity and CIN levels influence tumor cell fate and drug sensitivity.

18 citations

humanDNA methylation

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