Emil Marklund

This study links in vitro transcription factor affinities to in vivo single-molecule chromatin states using thermodynamic models and experimental data for KLF1.

This paper introduces a high-throughput method to measure DNA melting and develops models to improve DNA folding thermodynamics predictions.

This study investigates how mutations in the hinge region of LacI affect binding stability and inducibility, showing a trade-off between binding strength and inducibility rather than speed and stability.

This study links transcription factor binding to gene expression by analyzing chromatin configurations using single-molecule footprinting in human cells.

This study measures the rotation-coupled diffusion of LacI along DNA, finding it moves ~50 base pairs per revolution, supporting a facilitated diffusion model.