Author

Philémon Sirven

InsermORCID 0000-0002-1179-4972Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:imaging· 1

Frequent Co-Authors

André Nicolas· 1 shared Anne Vincent‐SalomoniD· 1 shared Chiara Bernard· 1 shared Christina MetoikidouiD· 1 shared E. RomanoiD· 1 shared Hélène SalmoniD· 1 shared Joseph AckermanniD· 1 shared Laëtitia LesageiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

André Nicolas

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintDec 22, 2025

Analysis of intratumoral immune heterogeneity reveals spatial organisation of immunosuppression in breast cancer

Christina Metoikidou, Pierre‐Emmanuel Bonté, Vadim K Karnaukhov…·Sebastián Amigorena

This study maps spatial immune heterogeneity in luminal breast cancer, showing progressive immunosuppression from tumor margins to core.

DOI 10.64898/2025.12.18.694622

𝕏 PostBluesky

BiophysicseLifePeer-reviewedNov 25, 2024

How cancer-associated fibroblasts promote T-cell exclusion in human lung tumors: a physical perspective

Joseph Ackermann, Chiara Bernard, Philémon Sirven…·Martine Ben Amar

The paper models how cancer-associated fibroblasts in lung tumors create barriers that exclude T-cells, affecting tumor growth and immune response outcomes.

11 citations

𝕏 PostBluesky