Author

Joel Celio Francisco

National University of SingaporeORCID 0000-0002-1229-0047Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

David M. VirshupiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

1 paper

Recent·Most cited

Cell BiologyJournal of Biological ChemistryPeer-reviewedMay 20, 2024

Hierarchical and scaffolded phosphorylation of two degrons controls PER2 stability

Joel Celio Francisco, David M. Virshup

This study investigates how two degrons in PER2 regulate its stability through phosphorylation by CK1, revealing that D1 acts as a backup degron and enables scaffolded phosphorylation in PER1:PER2 dimers.

13 citations

humanproteomics

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