Author

Marjolein T. Oostrom

Pacific Northwest National LaboratoryORCID 0000-0002-1296-9084Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1 Approach:large language model· 1 Assay:metabolomics· 1

Frequent Co-Authors

Bobbie‐Jo Webb‐RobertsoniD· 1 shared Jason McDermottiD· 1 shared Jaydeep P. BardhaniD· 1 shared Kasey Bowyer· 1 shared Kelly G. StrattoniD· 1 shared Lisa BrameriD· 1 shared Lummy Maria Oliveira MonteiroiD· 1 shared Michael A. MuniakiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperNeuroscience

Bobbie‐Jo Webb‐RobertsonORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintApr 17, 2026

PathwaySeeker: Evidence-Grounded AI Reasoning over Organism-Specific Metabolic Networks

Lummy Maria Oliveira Monteiro, Niaz Bahar Chowdhury, Marjolein T. Oostrom…·Jaydeep P. Bardhan

PathwaySeeker uses AI to reason about organism-specific metabolic networks using proteomic and metabolomic data, distinguishing confirmed reactions from hypotheses.

DOI 10.64898/2026.04.14.718256

non-human primateproteomics

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NeurosciencePLoS ONEPeer-reviewedMar 29, 2024

Fine-tuning TrailMap: The utility of transfer learning to improve the performance of deep learning in axon segmentation of light-sheet microscopy images

Marjolein T. Oostrom, Michael A. Muniak, Rogene M. Eichler West…·Bobbie‐Jo Webb‐Robertson

This paper improves axon segmentation in light-sheet microscopy images by fine-tuning the TrailMap model with expert-labeled data, achieving better recall and adjusted F1-score.

5 citations

mouseimaging

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